Cannabinoid Receptor 1
A cannabinoid receptor antagonist, also known simply as a cannabinoid antagonist or as an anticannabinoid, is a type of cannabinoidergic drug that binds to cannabinoid receptors (CBR) and prevents their activation by endocannabinoids. They include antagonists, inverse agonists, and antibodies of CBRs. The discovery of the endocannabinoid system led to the development of CB1 receptor antagonists.
Cannabinoid Receptor 2
Cannabinoid receptors are of a class of cell membrane receptors under the G protein-coupled receptor superfamily. Cannabinoid receptors are activated by three major groups of ligands: endocannabinoids, produced by the mammillary body; plant cannabinoids (such as Cannabidiol, produced by the cannabis plant); and synthetic cannabinoids (such as HU-210). All of the endocannabinoids and plant cannabinoids are lipophilic, such as fat soluble compounds.
α-Terpineol, terpinen-4-ol, and 4-terpineol are three closely related monoterpenoids. The aroma of terpineol has been compared to lilacs and flower blossoms. Terpineol is often found in cannabis varieties that have high pinene levels, which unfortunately mask the fragrant aromas of terpineol.
Terpineol, specifically α-terpineol, is known to have calming, relaxing effects. It also exhibits antibiotic, AChe inhibitor and antioxidant antimalarial properties.
A Few Facts About Terpineol
Terpineol is used in many everyday products such as lotions, soaps, and creams. It is a naturally occurring alcohol and has a distinct lilac odor. Terpineol is usually derived from pine oil, cajuput oil, and petitgrain oil. It is also one of the primary aroma ingredients in lapsang souchong tea. Pine smoke is used to dry this tea and creates the terpineol at the same time.
While it does occur naturally, terpineol is also frequently manufactured using alpha-pinene which is more readily available. Pinene is a thick, colorless hydration liquid which also has the pronounced lilac odor. It dissolves easily in alcohol and can also be dissolved in a mixture of glycerol and water. It provides a very stable base for other products including cosmetics, perfumes, and makeup.
Terpineol also belongs to a group of fragrant essential oils called terpenes. These can be found in the flowers of the cannabis plant. There is increasing interest in these substances among consumers, producers and researchers as they seem to offer some medical benefits.
Terpineol, geraniol, and valencene are three of the primary terpenes found in the cannabis plant. Terpineol refers to four monoterpene alcohol isomers which are found in combination in more than 150 plants. This includes the cannabis plant. Terpineol is frequently seen in plants which also contain high amounts of pinene, but because pinene has such as potent fragrance, it can often be difficult to detect the more delicate aroma of terpineol.
Terpineol is often used in products to add fragrance. These include lotions, soaps, and perfumes. It also contributes to the pine aroma of lapsang souchong tea. Terpineol boils at a very high 424 degrees Fahrenheit.
It occurs naturally in pine trees, cannabis, lilacs, eucalyptus sap and lime blossoms. It is also known for its ability to relax users. Research studies on mice also indicate decreased motility. The substance has come indicated medical benefits. It appears to be effective as an antibiotic, antitumor, antioxidant, antimalarial, anti-inflammatory and anxiolytic.
Two other terpenes found in the cannabis plant are geraniol and valencene. Geraniol is also found in geraniums and helps provide the blossom's distinct scent. It is frequently used as a flavoring agent and as an aromatic in body and bath products.
Valencene is another terpene found in both the cannabis plant and in valencia oranges. It has a sweet, citrusy aroma and provides the flavors of tangerines, grapefruits, and oranges.
Terpineol is one of the three primary terpenes found in cannabis. It is used to add aroma and flavoring to many different products.
Strains that often test high in terpineol include Girl Scout Cookies, and OG Kush
Terpineol’s potential medical benefits include: